Maestro Karen Sargsyan is a most notable Armenian choirmaster. From 1972 to 1980 Mr Sargsyan directed the choir of Yerevan State University and performed numerous concerts around former Soviet Union States, including the Baltic States, Moscow and St. Peterburg. Simultaneously, he directed the choir of the church in Holly Echmiadzin.
In 1989 Mr.Sargsyan has founded the Male Choir and performed the concerts in Germany (1989, 1990, 1991, 1992, 1993). In 1993 he was invited by the Armenian Diaspora of Sydney, Australia to lead the "Komitas" Choir and the "Sydney Symphonic Orchestra".
Since 1994, Karen Sargsyan is a principal choirmaster of the Armenian National Opera Theater. Under his direction the choir has been performed in Moscow (1995), USA (1999), Spain (1999, 2000), Lebanon (2001) and more.
During his work at the Theatre Mr. Sargsyan has been involved in a productions of such operas as Otello", "Il Trovatore", "La Traviata", "Aida" by G. Verdi, "Polievkt" by G. Donizetti, "Paliaggi" by R.Leonkavallo, “Anush” by A.Tigranyan, “Arshak the 2nd” by T.Chukhadjian, "Aleko" by Rachmaninoff, as well as several avant-garde productions.
Since 1995 he has periodically worked in Aleppo, Syria, where he has recorded a full version of Armenian Liturgy by M.Ekmalian.
In 2006, by the decree of the President of Armenia Robert Kocharyan, has been awarded the title of "Honoured artist of Republic of Armenia".